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Previous Topic | Next Topic  Acetaminophen metabolic pathway 




 
Kaplan Qbank USMLE



Author7 Posts
  #1

Which process shares the same metabolic pathway ?

a.-deamination of D-amphetamine
b.-formation of minoxidil sulfate
c.-hydrolysis of acetylsalicylic acid
d.-N-Dealkylation of desipramine
e.-N-Hydroxylation of meperidine

  #2

b???


  #3

b

firstly the reaction shown is a sulphation or phase ii reaxn

secondly hydroxylation is a phase 1 reaction, so are Ndealkylation, hydroxylation and de amination . hence being the same we can exclude these


___________________
If you yourself are at peace, then there is at least some peace in the world.

  #4

infact if hepatic stores of sulfate, glucuronide annd glutathione are depleted, or phase I enzymes have been induced, acetaminophen is metabolised to a toxic product

___________________
If you yourself are at peace, then there is at least some peace in the world.

  #5

thanks this question was WAS a headache

NO more !

B.-formation of minoxidil sulfate

  #6

sorry forgot to mention in my other posts ...data confirmed in Katzung

No more, i promise


___________________
If you yourself are at peace, then there is at least some peace in the world.

  #7

Thanks for clearing this up







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