asmi
Forum Hero
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Name the hormone which can increase the total (bound + free) cortisol without increasing the free cortisol ?
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| Julia
Forum Newbie
Topics: 1
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Estrogen stimulates cortisol-binding protein, CBP synthesis. In pregnancy estrogen goes up, more CBP, more cortisol bound to CBP, less free cortisol, more ACTH released in response, free cortisol level restored with CBP bound cortisol still being elevated.
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| asmi
Forum Hero
Topics: 1043
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good,thanks Julia!
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can anybody name cortisol binding protein?
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| asmi
Forum Hero
Topics: 1043
Posts: 4,609
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Transcortin
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| asmi
Forum Hero
Topics: 1043
Posts: 4,609
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So if any young female( female of reproductive age group) if she has increased plasma ACTH, Increased CBG, increased Total cortisol but normal free cortisol.............always points to pregnancy or OC pills.
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