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Kaplan Qbank USMLE



Author5 Posts
  #1

Which of the following modifications of an endogenous pharmacologically active peptide would be most likely to slow the metabolism of the peptide,thus decreasing its clearance and increasing its half life ?

a.-administering the peptidde with an enteric coating
b.-decreasing the number of amino acids in the peptide
c.-ensuring a free amino group at the N terminal
d.-ensuring a free carboxyl group at the C terminal
e.-sustituting a D for an L amino acid

  #2

Is it E??

  #3

I think so

  #4

E.-substituting a D for an L amino acid

  #5

why??? Explain please? rolling eyes

Edited by Musuq on 10/21/06 - 11:48 AM







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