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Kaplan Qbank USMLE



Author16 Posts
  #1

A 45 yaer old woman who has acute diverticulitis develops severe hypotension,tachypnea and tachycardia
she subsequently develops cyanosis and hypoxemia unresponsive to oxygen therapy
X ray films of chest shows a diffuse alveolar infiltrate
blood culture grows Escherichia coli
a major factor in the pathogenesis syndrome is

a.-degranulation of mast cells
b.-delayed type IV hypersensibility to bacterial products
c.-increased surfactant production by type II pneumocytes
d.-production of antibodies to alveolar basement membranes
e.-release of oxygen free radicals from sequestered neutrophils

  #2

I think is D

  #3

maybe septicemia ?

  #4

e

  #5

YES E

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  #6

I THINK IT IS E TOO-MHP Y DO U THNK ITS D

  #7

we cant explain all syptoms from d it must be something other than d

  #8

its definitely E.

neutros are involved in the pathogenesis of ARDS

in D the pt shud have had hemoptysis and renal complaints--consistent with goodpastures syndrome. this patient had RDS due to septicemia


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  #9

d

  #10

its e

tha disease is ARDS caused by free radical injury


  #11

YUP its definitely E

ARDS = MCC Endotoxin shock

Ecoli is the MCC of Septic Shock n the damge to the Alveolar membrane is due to Aggregation of Neutrophils n Macrophages. the initial injury is of Neturophils n is Free oygen radicals n Complement system activation which leads to the sequelae of intestitial difffusion n fibrosis


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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."

  #12

YUP its definitely E

ARDS = MCC Endotoxin shock

Ecoli is the MCC of Septic Shock n the damge to the Alveolar membrane is due to Aggregation of Neutrophils n Macrophages. the initial injury is of Neturophils n is Free oygen radicals n Complement system activation which leads to the sequelae of intestitial difffusion n fibrosis


___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."

  #13

I agree, E
it's ARDS so the damage is made by neutrophiles

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  #14

smiling face

  #15

neutrophils damage capillary wall by release of oxygen free radicals and cytokines.

  #16

E

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