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nbme

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MHP
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07/05/06 - 10:36 AM

10. A protein contains a 30-amino acid structural motif with four cysteine residues coordinated to a zinc atom. In which of the following is this structured motif most likely to be found?
A) Nucleosome
B) Ribonuclease
C) Ribosome
D) Spliceosome
E) Transcription factor

star1
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07/05/06 - 01:59 PM

E transcription factor

MHP
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07/05/06 - 03:56 PM

Why? can you please explain the answer please?

robin082006
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07/05/06 - 06:29 PM

ZInc finger motifs are associated with transcriptoon factors ( explained in Kaplan)

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MHP
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07/05/06 - 07:57 PM

thanks

Musuq
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07/05/06 - 11:05 PM

Zinc fingers are small protein domains in which zinc plays a structural role contributing to the stability of the domain. Zinc fingers are structurally diverse and are present among proteins that perform a broad range of functions in various cellular processes, such as replication and repair, transcription and translation, metabolism and signaling, cell proliferation and apoptosis. Zinc fingers typically function as interaction modules and bind to a wide variety of compounds, such as nucleic acids, proteins and small molecules.

Musuq
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07/05/06 - 11:08 PM

[img][url="http://rds.yahoo.com/_ylt=A9gnMiZsm6xEygMBMBWjzbkF;_ylu=X3oDMTBsNXZtZnJjBHNlYwNwcm9mBHZ0aWQDSTk5OV83Mw--/SIG=12onjft2d/EXP=1152249068/**http%3a//departments.oxy.edu/biology/Stillman/bi221/103000/notes.4.gif[/IMG" target=_blank

Edited by Musuq on 07/05/06 - 11:13 PM

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