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Author35 Posts
  #1

lets try to figure out the rationale of antiaarythmics by thiss thread

any one who can think up classic clues in the question pointing to a given antiarrythmic,,pLEASE POST..

i'll start


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  #2

1.yellow green halos in the visual field..tioxicity of

2. doc for arrythmias following attempted cardioversion

3.doc for av nodal arrythmias with half life of lesss than 30 sec







1.digoxin

2.lidocaine

3. adenosine


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  #3

4. why is digoxin contraindicated in WPW syndrome?



4. coz it wud increase the chances of conduction down th aberrant pathway and hence increase Ventricular rate


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  #4

which drug needs prior digitilization prior to administration and why?

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  #5

Which drugs are contraindicated in WPW?

  #6

CLASS 1 a --quinidine, procainamide, Disopyramide, amadiorone

AP increased

ERP increased

QT incresed.

USES-- ATRIAL AND VENTRICULAR ARYTHMIAS.



Class IB- lidocaine (iv) ,maxiltene,tocainide (orals)

AP decreased

USED--VENTRICULAR ARYTHMIAS ( post MI and DIGITALIS induced arythmias)



Class 1C flecainide. encainide, propafenone

NO affect on AP

specifically act on PURKINGE FIBRES. ALSO pro arythmogenic.

USES---V-tachycardias

USES


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  #7

class II beta blockers--

mechanism--- dcerease c AMP

decrease CALCIUM currents.

decrease SLOPE 4

av NODE SENSITIVE-( decrease SA/ AV node)- inc PR interval

uses-PROPHYLACTICALLY POST MI, PSVT, ventricular arythmias


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  #8

CLASS I and III DRUGS ACT ON CARDIAC MUSCLE TISSUES..

CLASS II and IV ACT ON SA/AV NODES..


  #9

Drugs contraindicated in WPW syndrome=digitalis,Ca channel blockers...

Plz add more to it..


  #10

which drug needs prior digitilization prior to administration and why?

__________



  #11

well the answer is quinidine. it has antimuscarinic side effects which can increase hr and tachycardia. also alpha block--vasodilation--reflex tachy

hence need initial digitalization to slow av conduction


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  #12

drugs which increase the refractory period in the normal av conduction pathway more are likely to INCREASE ventricular rate in WPW. this is because conduction will now occur along the aberrant pathway

hmm the question is wha twud u give in WPW?

(i dont the answer to this one btw)


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  #13

and btw is there a problem using using digoxin and quinidine together?

yes

what? quinidine inreases digoxin toxicity!!

thanx ppl for joining in


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  #14

VERy AMbitious QUeen

interacts with Digoxin

Verapamil, amiodarone, quinidine inrease digoxin levels hence chance of toxicity


Edited by study_ing on 07/05/06 - 04:20 PM

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  #15

drpkaur wrote:
Drugs contraindicated in WPW syndrome=digitalis,Ca channel blockers...

Plz add more to it..



and Beta Blockers

Treatment WPW: quinidine


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  #16

classes IA and III increase APD and ERP

classes II and III decrease conduction thru AV node


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  #17

can amiodarone be used for acute treatment of palpitations due to arrythmia?




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  #18

atleast guess..

cum on any newbie




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  #19

class Ib decreases the APD and ERP by shortening phase 3

notorious phenytoin{Ib} is DOC for dig induced atrial and ventricular arrythmias


Im with you "studying" this topic is important.


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  #20

thanx mjl1717

for drug induced ventricular arrythmias we use lidocaine for sure.

we dont use amiodarone for acute management as it duz not have an immediate onset of axn.

and phenytoin for arrythmias? cud u please gimme ur link/source so i cud read up on it too

thanx


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