Atherosclerotic disease NBME 2 S2

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Atherosclerotic disease NBME 2 S2

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Cedrick
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07/04/06 - 01:40 PM

A 56 year old man with extensive coronary artery atherosclerotic disease has evidence of coronary vasoconstriction and myocardial ischemia
the most likely causes of the vasoconstriction is failure of the endothelial cell layer of the diseased coronary arteries to produce a substance with which of the following actions ?

a.-activation of Na channels
b.-closure of K channels
c.-opening L-type Ca channels
d.-stimulation of ATP accumulation
e.-stimulation of cyclic GMP accumulation

mjl1717
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07/04/06 - 01:42 PM

answer-e-related to the Viagramech of action.

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Cedrick
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07/04/06 - 01:43 PM

Sweet

E

waqastariq

07/04/06 - 03:41 PM

exactly.. its E

waqastariq

07/04/06 - 03:41 PM

drpkaur
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07/04/06 - 07:28 PM

It's E as NO is not synthesized by vascular endothelium and NO acts by stimulation of cyclic GMP formation-leads to vasodilatation..

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