A 68 year old man has had bradykinesis,cogwheel rigidity,decreased facial expression and a festinatiing gait for 5 years degeneration of the neurons for which of the following neurotransmitters is most likely involved ?
answer -d-dopamine from the locus ceruleus and substantia nigra, there could excess Ach also.
*associated with paralysis agitans and Meyersons sign
Deficiency of GABA and ACh could be Huntingtons with the CAG repeat
Too much NE could be related to pheochromocytoma or neuroblastoma in childhood
Serotinin -raphe nucleus
Edited by mjl1717 on 07/04/06 - 03:16 PM
___________________ Smell the coffee! "Is That an Osler move??"
star1 Forum Guru
Topics: 93 Posts: 826
07/04/06 - 02:52 PM
#4
HEY is it C ?
why u choose D?
mjl1717 Forum Hero
Topics: 955 Posts: 5,450
07/04/06 - 03:07 PM
#5
i answered something i knew incorrectly-just dont want this to happen during exam.in other words "silly mistake" typing too fast. answer is c-dopamine ___________________ Smell the coffee! "Is That an Osler move??"
robin082006 Forum Hero
Topics: 471 Posts: 5,125
07/04/06 - 03:07 PM
#6
C ___________________ The Key to Succeed is Patience.
Cedrick Forum Fanatic
Topics: 320 Posts: 1,928
07/04/06 - 03:07 PM
#7
yeah same here
Cedrick Forum Fanatic
Topics: 320 Posts: 1,928
07/04/06 - 03:08 PM
#8
DOPAMINE
mjl1717 Forum Hero
Topics: 955 Posts: 5,450
07/04/06 - 03:15 PM
#9
ill rectify my mistake a little:
phenylalanine to tyrosine- p. hydroxylase............ tyrosine to dopa- t.- hydroxylase
dopa to dopamine-dopa decarboxylase.............. dopamine to Norepi-dopamine-B-hydroxylase
Norepi to epi-PMNT with SAM............ COMT and MAO make the metabolic end products
hydroxylations use Vit C
___________________ Smell the coffee! "Is That an Osler move??"
waqastariq
07/04/06 - 03:36 PM
#10
yups its C I was wonderin the same when I scrolled down and saw answerin Cedrick with D
dopamine rules
waqastariq
07/04/06 - 03:37 PM
#11
glabellar reflex is Meyersons sign
mjl1717 Forum Hero
Topics: 955 Posts: 5,450
07/04/06 - 03:40 PM
#12
waqastariq wrote: glabellar reflex is Meyersons sign
