Present in CNS

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Present in CNS

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Cedrick
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07/03/06 - 12:47 AM

Over a period of 3 years a 40 year old man develops generalized,hyperkinetic movements abd progessive dementia and progressive dementia
his mother and one sister have similar disease,but his faher and another sister are healthy
which of the following lesions is most likely to be present in the central nervous system of the patient and his affected family members ?

a.-atrophy of caudate nuclei
b.-loss of pigmented cells in the sustantia nigra
c.-microglial nodules and multinucleated giant cells in the white matter
d.-neurofibrillary tangles in the cortical neurons
e.-spongiform changes in the cerebral cortex

robin082006
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07/03/06 - 01:11 AM

A HUNGTINTON

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Cedrick
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07/03/06 - 01:12 AM

for sure ?

Cedrick
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07/03/06 - 01:14 AM

waqastariq

07/04/06 - 03:25 PM

its A...

waqastariq

07/04/06 - 03:26 PM

study_ing
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07/04/06 - 04:50 PM

i agree with the answer

however cud any one point out which disease

c.-microglial nodules and multinucleated giant cells in the white matter

i cud figure out all the remaining ones

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mjl1717
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07/04/06 - 05:57 PM

study_ing wrote:
i agree with the answer

however cud any one point out which disease

c.-microglial nodules and multinucleated giant cells in the white matter

i cud figure out all the remaining ones

*AIDS dementia complex or AIDS encephalitis!

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Dr.Papez
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07/05/06 - 03:56 AM

any chronic viral infection can lead to this findinf.. AIDS is a classical e.g
b-Parkinson's ds.
d- Alzheimer
e- CJD

vanshita
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07/05/06 - 08:19 AM

#10

which disease is spongiform nuclei in cerebral cortex

Dr.Papez
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07/06/06 - 03:23 AM

#11

CJD-creutzfeldt Jacob disease

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