Cedrick
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An adult's hemoglobin is 98% saturated with oxygen,but arterial oxygen is decreased
the most likely cause of this condition is ?
a.-anemia
b.-an arteriovenous shunt
c.-hemoglobinopathy
d.-high altitude hypoxia
e.-pulmonary diffusion defect
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| Cedrick
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| Cedrick
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anemia
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| dr_sarim
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agree anemia
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| Diego Casali
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In anemia, pO2 is normal!
There is only a decrease in hemoglobin!
So, anemia can't be the cause of a low pO2 with a normal hemoglobin.
I think D is the correct answer.
In high altitude hypoxia, you will have a normal Hb saturation (right shift) and a low pO2 (hypoxemia).
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| robin082006
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A
the question gives info about total oxygen, not PaO2
In Anemia, total oxygen decreased but PaO2 normal.
In Altitude, Hbsaturation decreased, total oxygen decreased in acute change and increased in acclimatized change
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| shumaker
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i will go with D
high altittude hypoxia
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| vamsi2004
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sorry michael schumacher!! its A and the reason given by robin is perfect
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| drpkaur
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I also agree with robin and vamsi..anemia is right answer..
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| veterana
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Anemia decreases Hb but arterial O2 is normal in anemia. In high altitude the O2 is low, and even when HB saturation is shift to the rigth (easier to give O2 to peripheral tissues) the capacity of saturation is normal, particularly at the extremes of the Hb-O2 curve. I think is D
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| waqastariq
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what I know is that ARTERIAL O2 is actually PaO2...thats what we get in ABGs...right?
and they call it arterial oxygen...so gues whoo is the right one [ ] nobody measures TOTAL OXYGEN in clinical settings or do they? 
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| somi78
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Anemia
Arterial oxygen content is determined by hemoglobin concentration, saturation and the pao2 all. Hb concentration is the most important factor. Hb saturation is normal in anemia, but since less hemoglobin less oxygen carried in the blood and since it's the most important contributor to arterial oxygen.. less arterial oxygen content. PaO2 Is normal in anemia and irrelevant for this question. Check out the oxygen dissociation curve on pg 270 in physiology it'll help!
Oxygen saturation is decreased in high altitude. kap physio 272
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| alpha12
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OK, here are the definition:
O2 content: total amount of O2 carried in blood
PaO2: amount of oxygen dissolved in plama.
So, which one is "arterial oxygen"?
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| Cedrick
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Ok
PaO2 is your "arterial"
did you get the question?
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| alpha12
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The final answer is D: high altitude hypoxia
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| docswapna
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alpha its A. plz read the explanations.
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| smal
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i think its A-V mixing,
coz here PA02 IS not decreased so PaO2 is not decreased.but due to A-V mixing,PO2 is decreased.
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| ssrpk
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oh cmon, A-V shunt does'nt hv any mixing effect, it only denotes tht arterial blood passes on to venous side without going thru capillaries!
answer is definitely A
thing is, its a bit wrongly worded tht's why so much confusion, besides it ain't no clinical setting, its only testing the concept!
and in high altitude setting, why wud there be a right shift???? person hyperventilates, which means low CO2, which will shift the curve to the left! later on with time 2,3 DPG compensates for it and it shifts the curve back to the right, but not to such extreme!
besides even if it does go to such extremes, hemoglobin will lose its affinity for oxygen in the pulmonary capillaries and the uptake will be reduced drastically!
one correction to wht robin described...."total oxygen decreased in acute change and increased in acclimatized change "
total oxygen actually increases but not due to acclimatization but due to increased production of RBC's i.e. polycythemia!
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| aim
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in anemia,hb conc ----------------dec, but Po2& saturation remains normal ---oxy content dec
in high altitude------po2&hb saturation dec-----oxy content dec
therefor ans is a
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| Addicudo
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An adult's hemoglobin is 98% saturated with oxygen,but arterial oxygen is decreased
the most likely cause of this condition is ?
PO2 = the Diffused O2 in the Serum .. which is the Oxygen to be exchanged at teh tissue level .. !!
Arterial Oxygen refers to the 02 content .. i.e the Total of the Diffused 02 and the 02 attatched to the Hb.
Option D .. High alt Hypoxia .. would lead to a Decreased P02 .. and also a decreased Hb Saturation .. !!
So the best option then is A) Anemia .. !
Hbpathies .. Ruled out simply as they would decrease the 02 saturation .. !
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