sonaliraj99
Forum Senior
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HELLO AL.. fa says MS is caused by destruction of oligodendrocytes.. goljan says.. t cel activity towards myelin.. pl clarify..ya big robbins says.. immune resonse towards myelin.. also wats d mechanism of GBS?? GUILLEN BARRE?
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| burdenbeat
Forum Newbie
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Well, MS infact is destruction of myelin. Myelin covers CNS cells. Since oligodendrocytes in part of the CNS, versus schwann cells in PNS, it is safe to say that destruction of myelin also causes destruction of oligodendrocytes. Its taking the simple concept one step further.
A step I question, wouldn't ask the simple definition of MS, being destruction of myelin, but rather take it one step further and apply it to a CNS cell (ie: Oligodendrocytes)
Here's a good linkage for you:
Question: In MS, what cranial nerve is most susceptible to being damaged???
Answer: CN 2 (Optic nerve). The optic nerve, is a nerve arising from CNS. This nerve is covered with myelin and hence explains why in most MS patients there is a loss of visual acuity.
See, this is a much easier question, but along the same lines to make the jump to answering Step I style questions.
Hope this helps, Good luck!!!
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