DrVirgo
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12. a 44 year old man presents to the physician because of a markedly inflamed and painful right great toe. He states that he just returned from a convention, an dhad noticed increasing pain in his right foot during his plane trip home. Physical examinatin is remarkable for swelling and erythema of the right great toe as well as small nodules on the patient's external ear. Aspiration of the MTP joint of the affected toe demonstrates needle-shaped negatively birefringent crystals. Which of the following agents would provide the most immediate relief for this patient?
A. Allopurinol
B. Aspirin
C. Colchicine
D. Probenecid
E. Sulfinpyrazone
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| reet
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C. Colchicine
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| DrVirgo
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Yes. why?
Can you say when the others would be used? thanks. 
And what about indomethacin?
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| leen
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C..
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| robin082006
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Colchicine for acute attack of gout
Probenecid for chronic gout
Allopurinol for increased uric acid due to chemotherapy
Aspirin and other NSAID for relieving pain.
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| disha
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why not aspirin?
itwould produce immediate relief
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| pocas
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C
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| DrVirgo
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When is Indomethacin used?
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| MHP
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the indomethacin mey be used as colchicine, in fact is most common used. But there isnīt in the answers.
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| study_ing
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duznt aspirin compete with uric acid in for secretion in the kidney...as far as my failing memory helps...probenecid duz too. it inhibits reabsorbtion but also competes for secretion..hence not used in an acute stage..comments please
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| pallav
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i think its aspirin
please be kind enough to tell the correct answer with explanation
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| study_ing
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ASpirin does increase uric acid levels.(source kaplan's explanation of a q )
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| star1
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FOR acute attack NSAID and Colchicine
FOR choronic attack Probenecid and allupurinol
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| docarchana
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its colchicine bcos aspirin causes hyperuricemia
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| fox
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OK so if Indomethacin was a choice, what would u pick b/w indomethacin & colchicin?
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| docarchana
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fox, colchicine is indicated for acute gout inflammation in kaplan. so i think its better to go with it. dunno about indomethacin. did u read redg it any where?
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