MDcooper
Forum Guru
Topics: 211
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How does sepsis decrease systemic vascular resistance?
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live and let live.
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| cyra
Moderator
Topics: 29
Posts: 844
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The interplay amongst the bacterial endotoxins(in case of gram negative bacteria) and exotoxins with the host immune system results in release of a large number inflammatory mediators...such as cytokines,interleukins(1 and 6 especially),TNF and a bunch of other vasodilators.This results in decreased peripheral vascular resistance.
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