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Kaplan Qbank USMLE



Author8 Posts
  #1

Light scope at 100x.

I see these huge clear cells which do not pick up iodine at all. These cells are generally tear-shaped (150-250 microns long) or slender and long (300 x 50 microns).

These huge clear tear-shaped cells always contain a variable number (3-12) of uniform small, oblong cells similar in form to yeast nuclei (15 X 7 microns - estimated, could be smaller -?). At times much larger yeast spores can also be seen. Iodine stains all this engulfed material bright purple.

These huge tear-shaped cells with small cells inside them always surround decaying parasitic material, but are not seen on the decaying vegetable matter.

What are these cells, both large and small?


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Edited by newbie on 06/26/06 - 01:33 PM

  #2

I've looked at thousands of O&P preps - they're NOT a parasite. What they are I couldn't tell you, however.

___________________
Clinical Microbiology since 1974

  #3

on.-is it human?

two.-however there is something on OBGYN

  #4

raised eyebrow

  #5

Cedrick wrote:
on.-is it human?

two.-however there is something on OBGYN

one.
The large cells are associated with a zoonotic parasite found in human gut. (This parasite has not been described so far.)

I am inclined to consider that the large cells are either symbiotic to this parasite or arise from the capsule of the giant cells of the parasite itself (not shown on the image). They appear essential for this parasite ability to fool and disrupt host immunity.

Ammonia is the main product of this parasite excretions. If these cells belong to a commensal, is there a protozoan that would thrive in ammonia and also devour yeast, bacteria, lymphocytes that would come its way?


two.
Could you please elaborate on OBGYN lead?

Thanks.

Edited by newbie on 06/27/06 - 02:59 PM

  #6

Check soon I wiil post

  #7

Thank you for your answer re Clue Cells posted on Vaginal discharge thread.

However,

1. the specimen in question is from intestines and not from vagina

2. the cells have distinct shape with clearly delineated margins unlike v.clue cells

3. material inside them is not bacteria (around 10 microns diam), kidney-shaped or much larger round yeast spores

4. material inside them is always at the center, rather than clinging to margins as in vaginal clue cells.

But. Is there an equivalent of clue cells in the intestines?


Edited by newbie on 07/01/06 - 07:23 PM

  #8

I know how to identify parasites in O&P preps. I have never studied cytology, so really can't help you out. Cytology is a totally different training cycle, and they take a different registry examination. This would obviously come under the realm of a pathologist also.

I have no idea whether there are clue cell equivalents in the intestines.

It would also help to post a REAL picture instead of a drawing of the cells you're trying to ID.


___________________
Clinical Microbiology since 1974







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