Cedrick
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A 32 year old man has a family history of bleeding.Partial thromboplastin and bleeding times are prolonged,aggregation of platelets with ristocetin is abscent,and factor VIII
{antihemophilic factor} concentration is decreased
The most likely diagnosis is
a.-deficiency of antithrombin III
b.-dissemianted intravascular coagulation
c.-hemophilia A
d.-hepatic failure
e.-von Willebrands disease
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| Cedrick
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is it C.-hemophilia A ?
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| nadiabarati
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e
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| Cedrick
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just checked it out
Choice C
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| robin082006
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E
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| eytanraz
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e
cedrick, just check out better
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| sridevibandaru24
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it is E
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| tn1kinobe
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von willenbrands present similar to hemophilia A.... but know that hemophilia A bleeding time is NORMAL. in VW, the bleeding time is prolonged. That's the key to answering this as E).
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| mediocre
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these are tricky qs. we have to memorise a few things for it;
High BT: v,l,d,p
High TT: h,d,l
High Aptt(Kcct): ALL except platelette defect/deficiency
High INR: h,k,l,d
key:h--heparin treated , d--DIC ,l--liver failure ,p--platelette defect
K---vit K defeciency v----von wilibrand factor def.
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| mediocre
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also remember,
low platelets-----l,d
Hemophilia is unique in that except for High Kcct,everything else is normal
For practical purposes ,Liver ds has almost normal ---TT,BT and Platlets
but it has High INR and APTT
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| mediocre
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these informations are handy for q s of this type
but the present q is straight forward
factor viii is decreased ------vwf or hemophilia
BT increased---------------- VWF(not in hemophilia)
so the answer is VWF
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| mediocre
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oops, I mean VWD
note: causes for highPT= causes for INR and so is the case for
Aptt and Kcct
...
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| klimt
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Great job mediocre, thanks
I chose vWD too on my nbme
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