mjl1717
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answer-a
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| nadiabarati
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in albinism we have loss of tyrosinase activity NOT absence of melanocytes, right?
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| mjl1717
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that may be true but i thought it may indirectly be related to absence of melanocytes?
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Smell the coffee! "Is That an Osler move??"
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| ndspider
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A
I looked this bugger up in langman's
Ichthyosis btw is one hell-of-a-way to go
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| robin082006
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A
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| nadiabarati
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please someone explain this Q!
it's not albinism BECAUSE melanocytes are right there and neural crest cells HAVE migrated!!
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| yonela78
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This is one tough and unfair q 
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| yonela78
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Although one can think that albinism links to melanocytes and then to neural crest cells, we know that albinism is a defect in tyrosinase and that has nothing to do with a defect in migration of neural crest cells
But...there is some syndrome called ABCD syndrome: an autosomal recessive syndrome characterized by albinism, black lock, cell migration disorder of the neurocytes of the gut (Hirschsprung disease), and deafness. And this is caused by a migration defect.
I found this info on http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?i...
I still think is an unfair Q. 
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| docswapna
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A is only appropriate
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| young_doc
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A. Straight out of First Aid.
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| Musuq
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A) Albinism
Kaplan, development of the fetal structures from the three germ layers. pg 105
Neural Crest Derivatives: NC migrate throughout the embryo and give rise to many different cells - Ganglia
- Cranial, dorsal root, sympathetic trunk
- Celiac, renal, plexus in GIT
- Glia, schwann cells
- Melanocytes (skin)
- Adrenal medulla (chromaffin cells)
Edited by Musuq on 11/26/06 - 12:40 PM
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| Jairmeto
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thanks for your graphs musuq, lol.
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