vallia
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A 24-year-old woman attempts suicide by taking an overdose of diazepam.
She is rushed to the emergency department, where the attending physician
will most likely order which of the following treatments?
A. Acetylcysteine
B. Atropine
C. Bicarbonate
D. CaNa2EDTA chelation
E. Deferoxamine
F. Ethanol
G. Flumazenil
H. Physostigmine
I. Pralidoxime
J. Protamine
Also the others are for....
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| suv
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POISON- ANTIDOTE
acetaminophen-acetylcysteine
organophosphorous poisoning-atropine and pralidoxime
iron and iron salts-deferoxamine
methanol and ethylene glycol-ethanol
benzodiazepenes-flumazenil
anticholinergics,antiparkinsonians-physostigmine
heparin-protamine
leadpoisoning backupdrug-EDTA
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| asherif
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G. Flumazenil
benzodiazepines antagonist
A. Acetylcysteine
used acetamenophen toxicity
B. Atropine
can be used in organo-phosporus poisoning
C. Bicarbonate
cause alkalanization of urine ==> enhance urinary excretion of acidic drugs (by increasing the ionization ==> decrease reabsorption
eg. acetly salcylic acid (ASA)
D. CaNa2EDTA chelation
used for chelation in heavy metal toxicity (eg. lead toxicity)
E. Deferoxamine
used to chelate Iron (Iron toxicity)
F. Ethanol
will enhance diazepam toxicity.
H. Physostigmine
Parasympathomimetic by reversibly inhibiting choline esterase enzyme
I. Pralidoxime
used early in organophosphorus poisoning to free cholinesterase enzyme before permenantly damaged.
J. Protamine
Protamine sulfate (derived from fish sperm or testis  )used in heparin toxicity
Edited by asherif on 06/22/06 - 09:47 AM
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| mjl1717
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also bicarb is the antidote for barbituate acid;;
EDTA, dimercaprol, succimer (in kids) penicllamine also for lead
dimercaprol (BAL) is fo arsenic , mercury, and gold,
nitrite, B12, and sodium thiosulfate is antidote for cyanide
methylene blue is antidote for methemoglobin
aminocapoic acid for tPA like meds
physostibmine for TCAs , phenothiazines atropin
pennicillamine for copper, arsenic and gold
i rest my case.
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| robin082006
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good listing.
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| suv
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physostigmine is NOT used for TCAs
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| mjl1717
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TCA's is controversial, I should have said succinylmoncholine and snake venoms involving tetrodotoxin.
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