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Kaplan Qbank USMLE



Author5 Posts
  #1

15. A 45-year-old woman comes to the emergency department because of a 10-hour history of fever, chills, and abdominal pain that radiates to her right shoulder blade. She has a history of cholelithiasis. Her temperature is 39.6°C (103.3°F), pulse is 120/min, respirations are 24/min, and blood pressure is 90/60 mm Hg. Abdominal examination shows tenderness in the right upper quadrant with guarding. Bowel sounds are decreased. Which of the following cytokines is most likely to be primarily involved in this patient's condition?

A ) Interferon-γ

B ) Interleukin-4 (IL-4)

C ) IL-10

D ) Transforming growth factor-β

E ) Tumor necrosis factor-α


  #2

One more cytokine question:
19. A 57-year-old woman with a ruptured appendix has septicemia and symptoms of septic shock. Blood cultures grow gram-negative rods. Which of the following cytokines is most likely to be responsible for the shock?

A ) Interferon-α

B ) Interferon-β

C ) Interferon-γ

D ) Interleukin-2 (IL-2)

E ) IL-4

F ) IL-7

G ) IL-10

H ) Transforming growth factor-β (TGF-βwink

I ) Tumor necrosis factor-α (TNF-αwink



  #3

15. ?? E (IL- 1/ TNF)
16. I
( Lipopolysaccharide in G - bacteria----> TNF----> IL- 1----> IL- 6/ IL- 8---> NO, PAF (high quantities)--------> shock

  #4

15. E?

16. I


  #5

Agree with both of you

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