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Kaplan Qbank USMLE



Author5 Posts
  #1

*what is the complex V of ETC ?

* How does oligomycin inhibits ETC ?

  #2

Complex V is the F0-F1 (ATP synthase). Oligomycin inhibits the ATPase reaction of the F1 complex

  #3

THX meg!

well yes oligomycin binds to the F0 of ATP synthetase.......inhibits dissolution of proton gradient...thus inhibiting both proton pump and ATP synthesis.

  #4

To which class of antibiotics does oligomycin belong to ?

What is rotenone?
Is it a poison or what?

  #5

Oligomycin incidently as I found on one website belongs to macrolides but does not function on 50s. (am not sure)
Rotenone is a fish poison put in lakes.







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