karusmle
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On routine annual screening, an asymptomatic 27-year-old man has PPD skin test. One year ago, a PPD skin test was negative. He works as a nurse. Three years ago, he was diagnosed with hepatitish A after a trip to South America. Examination shows no abnormalities. His serum aspartate aminptransferase (AST,GOT) acivity is 10 U/L, and serum alanine aminotransferase (ALT,GPT) activity is 14 U/L. An x-ray of the chest shows no abnomalities. Which of te following is the most appropriate chemoprophylaxis?
A) Isoniazid and folic acid supplementation
B) Isoniazid and rifampin
C) Isoniazid and vitamin B1(thiamine) supplementation
D) Isoniazid and vitamin B6 supplementation
E) No prophylaxis indicated
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| MAZI
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I THINK YOUR MEAN IS POSITIVE SKIN PPD TEST, IF IT IS TRUE THE CORRECT ANSWER IS A
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| shumaila
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if u mean positive skin test the correct answer should be D
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| AAAAA
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The student should start on prophylactic medication as soon as possible. The usual prophylactic regimen is isoniazid. The recommended duration of treatment is a minimum of nine months. Because of the hepato-toxicity of isoniazid, students will be monitored with liver function testing on a monthly basis. The student who has a positive skin test, a negative chest X-ray, and a normal exam, and who is otherwise healthy and receiving preventive treatment for tuberculosis infection, can return to all aspects of clinical care. The student who cannot take or does not accept a complete course of preventive therapy will have her/his work situation evaluated by the Associate Dean for Student Affairs of that student’s school to determine whether reassignment is indicated
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| AAAAA
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The correct answer is D
Peripheral neuropathy and CNS effects are associated with the use of isoniazid and is due to pyridoxine (vitamin B6) depletion, but is uncommon at doses of 5 mg/kg. Persons with conditions in which neuropathy is common (e.g., diabetes, uremia, alcoholism, malnutrition, HIV-infection), as well as pregnant women and persons with a seizure disorder, may be given pyridoxine (vitamin B6) (10-50 mg/day) with isoniazid.
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| AAAAA
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INH and pyridoxine (vitamin B6) is the correct answer
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| MAZI
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oh whats aterrible fault
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| AAAAA
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MAZI wrote:
oh whats aterrible fault
Folic acid would be in the OBGYN section in which folic acid is prescribed for pregnant patient to prevent malformation of fetus !
Don't give up, I have failed many, many examinations.
Try again, again , again, again, and again!!
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| AAAAA
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MAZI wrote:
Oh ! Whats a terrible fault !
Peripheral neuropathy and CNS effects are associated with the use of isoniazid and is due to pyridoxine (vitamin B6) depletion,
We all made mistakes !
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| infliximab
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D
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