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Kaplan Qbank USMLE



Author15 Posts
  #1

45. A 35-year-old man who takes street drugs intravenously develops fever, cough, and hemoptysis. X-ray film of the chest shows bilateral infiltrates. Echocardiogram discloses a 1-cm mass that is attached to the tricuspid valve. Blood culture grows yeast. The most likely causal organism is

A ) Aspergillus flavus

B ) Candida albicans

C ) Cryptococcus neoformans

D ) Histoplasma capsulatum

E ) Mucor species


  #2

B

  #3

ill go with cryptococcus

___________________
Smell the coffee! "Is That an Osler move??"

  #4

Among choices, only Candida, Cryptococcus, and Histoplasma may be yeasts--> exclude A and E

but Candida rarely causes pulmonary infection--> exclude B

Histoplasma often is seen in spelunkers while Cryptococcus in AIDS. This patient is an Intravenous drug abuser--> may be AIDS--> I go with C

so I too go with Cryptococcus. answer C

A ) Aspergillus flavus:Acute angle septate

B ) Candida albicans : yeast,, hyphae and pseudohyphae

C ) Cryptococcus neoformans : encapsulated yeast,

D ) Histoplasma capsulatum : hyphae with microconidia, yeast in tissue

E ) Mucor species :broad-angle non-septate hyphae



___________________
The Key to Succeed is Patience.

  #5

robin082006 wrote:
Among choices, only Candida, Cryptococcus, and Histoplasma may be yeasts--> exclude A and E

but Candida rarely causes pulmonary infection--> exclude B

Histoplasma often is seen in spelunkers while Cryptococcus in AIDS. This patient is an Intravenous drug abuser--> may be AIDS--> I go with C

so I too go with Cryptococcus. answer C

A ) Aspergillus flavus:Acute angle septate

B ) Candida albicans : yeast,, hyphae and pseudohyphae

C ) Cryptococcus neoformans : encapsulated yeast,

D ) Histoplasma capsulatum : hyphae with microconidia, yeast in tissue

E ) Mucor species :broad-angle non-septate hyphae



Good!: in addition Candida is actually normal flora but can flourish in the immunocompromised, commonly in HIV or IVDA its Candidiasis of the esophagus. You could REFLEXIVELY think Crytococccus in HIV or IVDA. Histoplasmosis is usually near Ohio/Mississippi River Valley. Mucor, I think Diabetes. {for those who are not aware Im associating IVDA with HIV since this is how USMLE would wantyou to think!}

Edited by mjl1717 on 06/18/06 - 08:22 AM

___________________
Smell the coffee! "Is That an Osler move??"

  #6

cryptococcus neoformans

___________________
eva

  #7

For the record, about a year or so ago I had a blood culture turn positive on day four. Gram stain showed yeast. I called the doctor and the patient was a drug abuser that had signed herself out AMA (against medical advice). Blood culture subsequently grew C. neoformans. I believe patient was also HIV positive.

Aspergillus would not show up as a yeast - it is not dimorphic. Likewise, Mucor is not either. Based on my experience in the lab, I would go with C. neoformans.


___________________
Clinical Microbiology since 1974

  #8

B for sure

Candida albicans

Infective Endocarditis in IV drug abusers and immunocompromised

  #9

yes its B.
IE in IV drug abusers- MCC are staphaureus,candida

  #10

thanx - didn't know there is a correlation between iv drug abuse and candida!

___________________
Traveler, there are no roads. Roads are made by walking.

  #11

docarchana wrote:
yes its B.
IE in IV drug abusers- MCC are staphaureus,candida



___________________
JSK .. O Lord !! Increase my capacity to Absorb knowledge ..

  #12

yup,candida.

___________________
remedy for weakness is not brooding over it ,but thinking of strength.

  #13

It is B - it is in the First Aid.

  #14

candida cause right sided infective endocarditis in iv drug abusers if he is immunocompromised

  #15

think is B







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