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drkirangm
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01/13/04 - 01:08 AM             #1

whats the mechanism of action of metronidazole?is there any reason why it acts particularly on anaerobic bacteria :?

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mjl1717
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01/13/04 - 07:33 AM             #2

metronidazole has a nitro group that removes electrons from FERREDOXIN (present in anaerobes) in a redox reaction. The resultant compound binds to both DNA and proteins and is cytotoxic.

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meg
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01/13/04 - 08:56 AM             #3

THANKS!!! grin

drkirangm
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01/13/04 - 12:17 PM             #4

thanQ smiling face

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