DrVirgo
Forum Hero
Topics: 1096
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Aspirin irreversibly inhibits COX in platelets.
What effect does this have on TXA (thromboxane), PGE prostaglandins), and PGI (prostacylins)?
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| HILFIGER
Forum Senior
Topics: 22
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I think decrease
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| drpkaur
Forum Guru
Topics: 196
Posts: 810
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thromboxane is a platelet aggregator right and aspirin is antiplatelet aggregator so it inhibits the synthesis of thromboxane..
aspirin inhibits the formation of PGE (prostaglandins) and PGI2 by inhibiting COX 1 and 2-non selectively
so aspirin decrease the formation of TXA2,PGE ,PGI2..
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| DrVirgo
Forum Hero
Topics: 1096
Posts: 3,515
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Please see this question:
http://www.prep4usmle.com/forum/thread/35613
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