vikramjit
Forum Newbie
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hi all,
a patient taking warfarin develops hemorrhagic skin necrosis.
do we jump to the conclusion that he has heterozygous Protein C deficiency (a la Goljan HY), or can this happen normally since Protein C has a shorter half life compared to other Vit K dependant coagulation factors, hence gets inactivated quicker ?
thanks,
vikramjit
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| tolito
Forum Fanatic
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a la goljan hy, i think this occurs in the first week so one gives heparin along with warfarin and keep warfarin dose low.???
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| tolito
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more info
http://www.medscape.com/viewarticle/451073_2
it does happen within 10days and is related to protein c, s deficiency and some other stuff as indicated in this article.
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| vikramjit
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Topics: 4
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thanks tolito for the prompt n comprehensive reply, sure did clear out the mess.
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