DrVirgo
Forum Hero
Topics: 1096
Posts: 3,515
|
A 77 year old man had repeated episodes of difficulty speaking, facial numbness, and clumsiness of the left hand. Dopler sonography of his carotid arteries shows no abnormalities. Which of the following drugs is the most appropriate therapy to prevent future episodes:
A. Aspirin
B. Diflunisal
C. Methyl Salicylate
D. Olsalazine
E. Salicylic acid
F. Salsalate
G. Sodium salicylate
H. Sulfasalazine
Please give the answer, explain, and state what the other drugs are used for. Thanks. 
___________________
Our greatest glory is not in never falling, but in rising every time we fall.
|
| robin082006
Forum Hero
Topics: 471
Posts: 5,123
|
I guess A
This patient may have TIAs (transient ischemic attacks)
Among the choices, only Aspirin is used in TIAs
___________________
The Key to Succeed is Patience.
|
| drpkaur
Forum Guru
Topics: 196
Posts: 810
|
the answer must be A..
Diflunisal -it's a diflurophenyl derivative of salicylic acid,it is not metabolized to salicylate and therefore cannot cause salicylate intoxication ..it is 3-4 fold more potent than aspirin as an analgesic and an anti-inflammatory agent but it has no antipyretic properties..it does not enter CNS ,therefore cannot relieve fever..
Sulfasalazine -sulfa drug.others are salicylates..
|
| mjl1717
Forum Hero
Topics: 958
Posts: 5,463
|
as long as there is no gastric sensitivity Ill keep it simple with--aspirin
Ill take one: sulfasalizine can exhibit synergy, inhibits dihydrofolate reductase when you push PABA. has an adverse effect of photosensitivity. As drpkaur said: the others are fancy ways of saying salicylate. {irreversibly inhibiting cyclooxygenase.}
Edited by mjl1717 on 06/10/06 - 08:55 AM
___________________
Smell the coffee! "Is That an Osler move??"
|
| DrVirgo
Forum Hero
Topics: 1096
Posts: 3,515
|
Isn't aspirin a salicylate too!?!? (same as acetylsalicylic acid)?
___________________
Our greatest glory is not in never falling, but in rising every time we fall.
|
| robin082006
Forum Hero
Topics: 471
Posts: 5,123
|
yes Aspirin is Acetylsalicylate
MethylSalicylate is dermally used pain reliever(Salonpas)
___________________
The Key to Succeed is Patience.
|
| DrVirgo
Forum Hero
Topics: 1096
Posts: 3,515
|
Ok, so A?
___________________
Our greatest glory is not in never falling, but in rising every time we fall.
|
| Cedrick
Forum Fanatic
Topics: 322
Posts: 1,986
|
Yeah it is A
I had the same question and was very confused
but if you think about it aspirin still a very versatil drug,antipain
antipyretic, antiplatelet
Chioce A
and thaks for posting you helped me in my last block !!!
|
| robin082006
Forum Hero
Topics: 471
Posts: 5,123
|
in practice, doctors use Aspirin tablet (81mg, or 100mg but 81 mg is preferable) to prevent TIAs
___________________
The Key to Succeed is Patience.
|
| mjl1717
Forum Hero
Topics: 958
Posts: 5,463
|
there are some reports out that say an aspirin a day also decreases the incidence of colon ca.
___________________
Smell the coffee! "Is That an Osler move??"
|
| DrVirgo
Forum Hero
Topics: 1096
Posts: 3,515
|
Thanks everyone!
___________________
Our greatest glory is not in never falling, but in rising every time we fall.
|
|
| |
| | | | | | | | | | | |
