karusmle
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a 32 year old women who is HIV positive has a CD 4 + lymphocyte count of 800 /mm3 (normal = >500).her health maintence regimene include immunization against which of the following pathogens???
a)hemophilus influenza type b
b)hepatitis A
c)influenza virus
d)neiseeria mengitidis
e)streptococcus pyogens(group A)
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| achilles
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a-H. influenza type b ?
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| Jinx
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c-influenza
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| drsap
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c
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| mesh
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C??
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| AAAAA
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C
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| AAAAA
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Impact of Influenza Vaccine on Response to Vaccination with
Pneumococcal Vaccine in HIV Patients
The clinical effectiveness of 23-valent pneumococcal vaccine in human immunodeficiency virus (HIV)-infected
patients is controversial, because of the low immunological response in these subjects. We studied the clinical
response of pneumococcal vaccine and the relative impact of influenza vaccine by administering both pneumococcal
and influenza vaccine in a group of 150 HIV patients belonging to all CDC categories. In the group
of 90 HIV-infected patients vaccinated against both pneumonia and influenza virus, there was a low incidence
of mild influenza (13.3%) and no case of pneumococcal pneumonia. On the contrary, among 60 nonvaccinated
HIV patients, 61.6% underwent mild to severe influenza and two developed pneumococcal pneumonia.
23-valent pneumococcal vaccine (PV) seems to be clinically effective in preventing pneumonia in HIV-infected
patients, and even more if strengthened by influenza vaccine.
407
INTRODUCTION
THE INCIDENCE OF PNEUMOCOCCAL DISEASES such as pneumonia,
bacteremia, otitis, and meningitis, was increased in
patients infected by human immunodeficiency virus (HIV)
before the advent of highly active antiretroviral therapy
(HAART).1,2 The introduction of HAART has positively modified
this trend,3–6 and the protective effect of HAART seems
to be mediated by enhancing the humoral response to pneumococcal
antigens.7
The 2002 guidelines for standard immunization8 and for preventing
opportunistic infections9 among HIV-infected persons
recommended immunization for HIV patients with the 23-valent
pneumococcal polysaccharide vaccine (PV); Rodriguez-
Barradas et al.10 suggested vaccinating HIV patients early in
the course of the disease, before CD4 cell count falls below
200/mm3. However, these authors and others 11–14 showed a
modest immunogenicity of PV among HIV patients receiving
long-term HAART.
Recently, an altered pulmonary immunoglobulin response to
Streptococcus pneumoniae has been described in HIV patients.
15 Pneumococcal diseases are often a consequence of influenza
infection. To our knowledge there is no exhaustive report
on the clinical outcome of PV and influenza vaccination
among HIV-infected persons.
Aiming to clarify the clinical effectiveness of PV in minimizing
pneumococcal infections in HIV/AIDS patients and the
respective role played by influenza vaccination of coadministered,
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| AAAAA
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23-valent pneumococcal vaccine (PV) seems to be clinically effective in preventing pneumonia in HIV-infected
patients, and even more if strengthened by influenza vaccine.
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| AAAAA
Forum Fanatic
Topics: 156
Posts: 1,991
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Influenza vaccine not only prevents flu among HIV pt but also helps to prevent pneumonia !!!
AAAAA wrote:
23-valent pneumococcal vaccine (PV) seems to be clinically effective in preventing pneumonia in HIV-infected
patients, and even more if strengthened by influenza vaccine.
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