mjl1717
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If the stucture of pennicillin appears like a house, with a garage, with side chain, and methyl groups on the side of the house. where does beta lactamase attack.
a) the house
b)the methyl groups
c)the side chain next to the garage
d)the garage
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| study_ing
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look for th N uniting the wall of the house with the garage. basically the roof of the garage is the target(c-n) bond
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| mjl1717
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fast, you got it but my diagram shows the c-n bond is the floor of the house. and the c is double bonded to a oxygen
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| HILFIGER
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I think c-n bond is the floor of the garage
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| study_ing
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as long as we attack the correct group
i used figure v-1-1 from kaplan pharma but mrs shows otherwise...i hope its not an important detail
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| mjl1717
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excuse me I mean floor of the garage--its good to know where beta lactamase works
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| study_ing
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i meant as long as we can identify the n unitting the garage to the house, trace the c with the double boned o with it.
..
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| rm
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d. the garage
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| HILFIGER
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d is correct. For more details please refer to Basic and clinical pharmacology, 9th ed, page 736, 6-aminopenicillanic acid.
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