chalooch101
Forum Newbie
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In Hashimoto's a goiter develops from TSH stimulation, but why is I-131 uptake low if gland is being stimulated. Shouldn't the gland increase the I-131 uptake from stimulation?
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| study_ing
Forum Fanatic
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please do not confuse hashimoto's with graves.
in graves, antibodies are stimulatory. (accounts for 60-80% of hyperthyroidism)
in hashimotos they r not. infact it is a very common cause of goitrous, primary HYPOthyroidism
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| Slacker
Forum Elite
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I have a question Study_ing. is there a goiter in hashimoto. if yes, then is just due to the inflamation caused my the gland destruction??
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| study_ing
Forum Fanatic
Topics: 180
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yes. it is a very common cause of goitrous primary hypothyroidism. my guess would be that it is attributable to inflammation due to the autoimmune process. ( btw on histology we wud see patchy llymphocytic inflammation)
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