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Kaplan Qbank USMLE



Author5 Posts
  #1

Which of the following diseases is in herited in a autosomal codominant trait.

A. Osteogenesis imperfecta.
B. Central core disease
C. Prader-Wili Syndrome
D. Alpha-1-Antitrypsin
E. Pyruvate Kinase Def.

  #2

thats a new word to me

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  #3

Well you learn something new everyday!
This site tells you alittle about it.

Here is a snipit.

How do people inherit alpha-1 antitrypsin deficiency?
This condition is inherited in an autosomal codominant pattern. Codominance means that two different versions of the gene may be expressed, and both versions contribute to the genetic trait.

The most common version (allele), called M, produces normal levels of the alpha-1 antitrypsin protein. Most people have two copies of the M allele (MM), one from each parent. Two altered versions that produce moderately low or very low levels of alpha-1 antitrypsin are called S and Z, respectively. Individuals with two copies of an altered allele (ZZ or SZ) are likely to develop alpha-1 antitrypsin deficiency.



  #4

Very cool I did check the site

  #5

thanx ..that was valuable...me tot the codominant was a typing mistke!!


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