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Kaplan Qbank USMLE



Author4 Posts
  #1

Name the disease causing mutation in homeotic gene?

  #2

Waardenberg syndrome(deafness, altered facial skeleton and different iris colours between the two eyes)-involves PAX3 gene
Aniridia (PAX6)
any others?

  #3

Here are a few-there are many(the letters or # is the Homeotic gene)
Clustered-----Hox A-9 Acute myeloid leukemia
Hox A-3-Hypoparathyroidism

Non clustered--Gbx and Nkx3.1-Prostate cancer
Pax-3- KleinWaardenburg syndrome**
Pax-3-rhabdomyosarcoma

___________________
Smell the coffee! "Is That an Osler move??"

  #4

Thx!
Mjl I can feel your strength :idea:







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