AAAAA
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Which one is more reliable to make the diagnosis of Lupus?
A. ANA
B. nDNA
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| vallia
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anti-dsDNA
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| AAAAA
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Interesting answer but let me think again
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| Jinx
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anti-dsDNA
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| chemamr
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anti-ds DNA (and anti Sm) are more specific for lupus.
ANA is used for screening (sensitive) purposes.
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| AAAAA
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The most important criteria is
positive ANA.
Dr. Chemamr is correct !
A negative ANA always certainly rule out Lupus
Almosts 100% of ALL patients with Lupus are ANA positive.
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| AAAAA
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Let me explain this to you much more clearly.
because there are 11 criteria in making the diagnosis of Lupus, and we only need 4 at "any" time of the progression of the disease.
So most rhematologists will do a panel of tests including ANA, dsDNA ,ssDNA etc.
A negative ANA will rule out Lupus
But a positive ANA will not confirm Lupus
So ANA is used to "rule out" Lupus only !
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