vallia
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Before being approved by the FDA, a chemical is tested for
carcinogenicity by examining its mutagenic effects on bacterial
cells in culture. Which of the following tests is used to make
this determination?
A. Ames test
B. Nitroblue tetrazolium test
C. Watson-Schwartz test
D. Widal test
E. Woellner enzyme test
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| vanshita
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A
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| doc179
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A
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| leen
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A..
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| vallia
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yes A
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| guangyu
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what are the other test?
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| vallia
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The correct answer is A. The test described is the Ames test, which measures damage to DNA and correlates well with carcinogenicity in vitro. It is relatively inexpensive to perform, compared to other tests of carcinogenicity, and is frequently used as a screening test for potential carcinogens.
The nitroblue tetrazolium test (choice B) is used to examine the ability of neutrophils to undergo a respiratory burst, and is used in the diagnosis of hereditary immunodeficiencies.
The Watson-Schwartz test (choice C) detects porphobilinogen in urine, and is used in the diagnosis of porphyrias.
The Widal test (choice D) is used to diagnose typhoid fever.
The Woellner enzyme test (choice E) detects heterophil antibodies in patients with Epstein-Barr virus infection, such as infectious mononucleosis.
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| nadiabarati
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Please tell me how you knew the answer? I'd never heard of these tests!
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| tolito
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i know only widal ( we do it a lot in the tropics), and nitroblue. but i have memorised the answer!!! i came across the question in qbank.
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| nadiabarati
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thanks a lot tolito.
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| Cedrick
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Wow
Now you have me looking for this
ames test
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| chemamr
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agree with A.
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| doc179
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Ames test is mentioned in pharmacology under the topic Drug development and testing.
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| vallia
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yes this is from an older Qbank (2002), I also knew only about Widal and nitroblue
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