doc179
Forum Guru
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B ?
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| doc179
Forum Guru
Topics: 67
Posts: 1,217
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expression of RNAs means transcription and I could only think of B out of the choices. But not sure.
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| general malaise
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i agree B
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| nadiabarati
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expression of RNA doesn't mean translation? expression of DNA means transcription!
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| mjl1717
Forum Hero
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just to get the definitions correct:
RNA synthesis-transcription /// synthesizing protein- translation///synthesizing DNA from RNA-reverse transcription! 
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| nadiabarati
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I asked the meaning of RNA expression!! Not the meaning of things you wrote
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| doc179
Forum Guru
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nadiabarati I was also confused abt this, but this is what I know..expression of protein means translation( I am sure abt this ) so I thought expression of RNA means transcription.
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| nadiabarati
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thanks doc179
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| naperthrill
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I disagree with doc 179. By the way nadia This is a GREAT question. Actually i think it would have stumped anyone if you didnt read closely. I think i agree with what you stated originally. I tried to look up this definition online but without much luck but from what i did find this is what i think. DNA is expressed as RNA, so what affects DNA becoming RNA probably nuclear transcription factors. RNA is expressed as a protein so What affects that Ribosomes! I typed in "Rna expression" and Ribosome into google and it came up with a few journal articles looking into Ribsomes and RNA expression so i assume they must be tied together. Thanks for the question, that was definately a tricky one.
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| doc179
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in response to naperthrill's post:
I feel that RNA expression does not mean protein expression (which is what the ribosomes help do).
For example, if you express siRNA: the objective of producing siRNA is for it to go and destroy some other RNA. It was never meant to be translated. So here RNA expression is meant to result in RNA as an end product
Recent findings include RNA enzymes as well. So the end product can be RNA (again this RNA not intended to be translated into protein at all)
You will note that only mRNA gets translated. siRNA, tRNA, rRNA etc were never meant to be further translated. So RNA could be the end product. If you need a particular RNA, and you need the DNA to make it, what would you call the process.......lets see..... "RNA expression" I guess.....
Here is another link to back that idea up.
http://www.cbcrp.org/RESEARCH/PageGrant.asp?grant...
From this link, I have copied this sentence:
“Rats exposed at the peak of BRCA1 RNA expression or the nadir of RNA expression but the probable peak of protein expression show a delay in onset of tumor appearance and it takes much longer for all the tumors to appear.”
This clearly shows that RNA expression is not the same as protein expression. Sometimes protein expression can be high when its RNA levels are low.
Similarly, there are many genes that are transcribed into mRNA and not translated into protein until a much later time, as and when needed. Again, the RNA is expressed but that does not mean the protein was expressed as well.
To begin with, I too was not sure what RNA expression exactly meant. Now I feel it means the production of the RNA in question is RNA expression. (Just like protein expression means doing what it takes to make that protein).
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| naperthrill
Forum Newbie
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hmmmm. i think you actually are probably right then. The wording is quite tricky perhaps its just meant to be as straitforward as you make it seem. After all this isnt a kaplan questoin, its the NBME exam. Haha its like did the chicken come first or the egg? good work doc179, my bad that i disagreed at first. I think you make a good point and when i read the question again it does seem to be discussing whether an RNA is expressed not what i had originally wrote.
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