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Author3 Posts
  #1

CAN ANYONE CLARIFY THAT HIV does cross the placenta or not. In HY it says that it does, but I have seen a live operation on TLC that the surgeons use the technique of bloodless c-section of the hiv+ mother, so that her neoborn is not exposed to her blood via the normal route of birth canal, in short meaning that HIV + moms do not necessarily have HIV+ babies or that it can be prevented. According to this case senerio one wonders that then HIV cannot cross the placenta.
Your thoughts??

  #2

HIV load of the mother determines the risk of the foetus getting the infection. Though most of the transfer occurs during transplacental hemorrhage, the foetus can be infected in utero as it is exposed to infected amniotic fluid which it swallows. Also if the mother has any genital lesions (other STDs) then chances of exposure to virus is high. If the mother has a high amount of antibodies, then some protection is possible for the foetus.
Caeserian section and avoiding breast feeding decrease transmission chances.
The risk of getting infection is highest during the perinatal period but cases have been reported of aborted foetuses as early as 15 weeks with HIV infection in them. It varies from case to case.

  #3

Thanks meg!
By transplacental hemorrahge, one can assume that if the "bleeding occurs" i.e exposure to the maternal blood in the amniotic fliud, then HIV exposure occurs? meaning HIV virus itself cannot cross the placenta??
If not then do "larger loads of the virus" actually "change" the property of the virus not crossing the placenta?? I am stuck on this q because something like this appeared in my previous step1 attempt. Now I feel that If I am getting confused somewhere I have to clear it. HIV topic is now a Hot topic! So thanks for bearing with me!!
Majotity of bacteria cannot cross the placenta, some really bad viruses do, so we really have to know that whether HIV in small or large quantities,can or cannot cross the placenta itself, what do you think?







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