DrVirgo
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What is the right answer? 
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| robin082006
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C
Fkurocortisone is a meneralocorticoid: decrease serum K+, increase urinary K+, decrease serum renin.
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| DrVirgo
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Thanks. I couldn't find this drug listed in Kaplan Pharm... Is it in Kaplan notes? 
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| robin082006
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Not seen in Kap note but you'll see when reading explanation
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| Musuq
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I would go C)
So, we can assume that blood pressure will return normal after mineracolorticoids? I mean good enough to supress renin sinthesis?
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| NE
Forum Guru
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C
The physiologic action of fludrocortisone is similar to that of hydrocortisone. However, the effects of fludrocortisone, particularly on electrolyte balance, but also on carbohydrate metabolism, are considerably heightened and prolonged. In small oral doses, fludrocortisone produces marked sodium retention and increased urinary potassium excretion. It also causes a rise in blood pressure, apparently because of these effects on electrolyte levels. In larger doses, fludrocortisone inhibits endogenous adrenal cortical secretion, thymic activity, and pituitary corticotropin excretion: promotes the deposition of liver glycogen; and, unless protein intake is adequate, induces negative nitrogen balance.
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