DrVirgo
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16.
The increase in the intracellular concentration of AMP in muscle after 15 minutes of strenuous exercise has which of the following effects?
A
)
Increased activity of adenylyl cyclase
B
)
Increased breakdown of glycogen
C
)
Increased release of insulin
D
) Inhibition of PFK phosphofructokinase activity
E
)
Inhibition of pyruvate kinase activity
B??
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| robin082006
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| DrVirgo
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Thanks Robin. 
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| vamsi2004
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wats the answer plzzz...
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| MHP
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B. Increased breakdown of glycogen
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| pallav
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i think the answer is increased activity of adenyl cyclase
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| Musuq
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b)Increased breakdown of glycogen?
Glycogenolysis
A glycosyl (glucose) molecule is split off the glycogen, a Pi is added, and glucose-6-phosphate is formed. Note that this does not require any energy (ATP) input
During high-intensity exercise, glycogen supplies most of the glucose units breakdown of muscle glycogen is controlled by phosphorylase a through a series of events initially started by Ca2+ and increased [Pi] . [Pi] is an important stimulator of glycogenolysis.
However, other unknown modulators are also involved.
EPI (Epinephrine) activates Adenylate Cyclase which stimulates "cAMP" production and glycogenolysis...
+ cAMP, Ca2+, ADP, AMP, IMP, Pi
phosphorylase b (inactive) <======> phosphorylase a (active)
-- ATP, G-6-P, H+
Activation of phosphorylase a inactivates glycogen synthase
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| Musuq
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need to review
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