NBME Skeletal Muscle relaxant

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NBME Skeletal Muscle relaxant

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DrVirgo
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05/07/06 - 06:39 PM

2.

Which of the following drugs is a skeletal muscle relaxant that works by a direct action on excitation-contraction coupling rather than an effect on the central nervous system?

A ) Baclofen

B ) Benztropine

C ) Bromocriptine

D ) Dantrolene

E ) Diazepam

mechanism of action?

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robin082006
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05/07/06 - 06:59 PM

I go with D, blocks Ca++ release from muscle ER

A and E: centrally acting ralaxants

Bromociptine: Dopamine receptor agonist

Benztropine: muscarinic receptor antagonist

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drpkaur
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05/07/06 - 09:46 PM

I also go with dantrolene as it blocks Ca++ release release from muscle sarcoplasmic reticulum

yasmeen
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05/08/06 - 01:39 AM

D IS SIMPLY RIGHT

DrVirgo
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05/08/06 - 08:47 PM

I agree with D. smiling face

Thanks.

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