mjl1717
Forum Hero
Topics: 955
Posts: 5,451
|
Anyone know how to Dx and Rx the 2 most popular species of naegleria. (in order to prevent complications of amebic meningoencephalitis
___________________
Smell the coffee! "Is That an Osler move??"
|
| medchick
Forum Newbie
Topics: 3
Posts: 11
|
Dx relies upon microscopic observation of trophozoites from fresh CSF (or histological sections of CNS tissue) and then Rx with Amphotericin B and miconazole - however, as you probably already know, death occurs within a week in untreated patients
|
| bactitech
Forum Elite
Topics: 25
Posts: 494
|
Aha! You were watching "House" tonight 
Hopefully, you realize that this show is NOT what happens in hospitals in real life....
(I just love it when these docs go in and perform their own tests in empty laboratories with poor lighting and they get results within minutes or seconds...)
___________________
Clinical Microbiology since 1974
|
| mjl1717
Forum Hero
Topics: 955
Posts: 5,451
|
Thank you to both of you.
Yes I saw "House" bactittech. Glad you're still here! The boards could ask about someone swimming in a lake or stagnant pond and becoming infected with this particular organism.
___________________
Smell the coffee! "Is That an Osler move??"
|
| tolito
Forum Fanatic
Topics: 119
Posts: 2,164
|
good question, mjl1717. good answer, medchick. good observation, bacitech!!!
i watch telly and try to learn a new drug each day in case they bring it out!!!
by the way saw something on enteroviruses the other day
___________________
It has been a looooong hard journey but I am inches away from my destination...
|
| tolito
Forum Fanatic
Topics: 119
Posts: 2,164
|
more info
for naegleria fowleri (foul playing org is protozoa, acts like bacteria and treated with antifungal)
csf shows high neutrophil, low glu, high prot like bact mening but gram stain shows no org and culture grows no bact.
micro shows motile amoeba.
rx with antifungal, intrathecal amphotericin B.
for ACANTHAMEBA
csf exam shows cyst and trophozoite stages.
rx is difficult with many antifungal incl pentamidine.
it causes chronic granulomatous brain infection in immunocompromised ind unlike n.fowleri that causes death within a week.
source...MRS.
___________________
It has been a looooong hard journey but I am inches away from my destination...
|
| mjl1717
Forum Hero
Topics: 955
Posts: 5,451
|
yes tolito, good info, thats one reason I asked because its so lethal. Imagine innocently swimming swimming in a lake and expiring in a week.
___________________
Smell the coffee! "Is That an Osler move??"
|
| tolito
Forum Fanatic
Topics: 119
Posts: 2,164
|
i tell you when i read that bit while doing micro, i was glad i do not do lake or river swimming. i do it in the pool and i am no good at it anyway.
___________________
It has been a looooong hard journey but I am inches away from my destination...
|
|
| |
| | | | | | | | |
