determine
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You are considering treating a 21-year-old female with a history of anorexia nervosa and depression with an antidepressant. Which one of the following should you avoid?
1) desipramine
2) citalopram
3) venlafaxine
4) bupropion
5) phenelzine
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| achilles
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5-phenelzine
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| Rasul
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Bupropione. The reason is: eating disorders have in their pathogenesis seizure activity, and bupropione(Wellbutrin )is containdicated in seizures(and eating disoders,accordingly)
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| mesh
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4
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| yasmeen
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i think its phenelzine its mao inhibitor requires dietry restrictions
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| seri
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the way i approached it was to r/o options that are used in treatment i.e. 2 & 3. after that i wasnt too sure. ssri's increase serotonin levels in the synapse and can be used for treatment of depression and maoi's by inhibiting breakdown of these neurotransnitters may still be used. desipramine has the action of increasing norepinephrine and to a moderate extent serotonin too, so that leaves me with bupropion.
i'm curious to know the right answer and the explanation!
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| srf
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citalopram is sssi, will cause anorexia not a good choice in this case
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| msyamp
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hmm determine do you have answer?
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| drk1980
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i think Bupropion. for the same reason Rasul mentioned above.
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| AAAAA
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Common sense goes a long , long way !
You don't need to be a doctor to know the answer.
And Bupropion is the wrong answer !
Bupropion is a nicotine cessation drug and can cause weight gain. The secretary even knows about this !
So D is wrong
The correct answer is E
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| Diego Casali
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5. Phenelzine
If anorexia nervosa in this patient is subtype binge - eating/purging, she is likely to eat many foods that can interact with MAOI's.
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| drhyd
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Bupropion is correct.
And AAAAA is rt that its used for smoking cessation and even buspiron is also used for smoking cesation and both decrease craveing for nicotine.
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| HighHopes
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Bupropion for Sure
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| alenka
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i'd say
5-phenelzine-
with bupropion it's clear-may cause weght gain.but it's not that life-threatening.
but with drug-food interaction if you put her on MAOI-it's pretty dengerous.
what's the right answer,determine?
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| HighHopes
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Bupropion decreases the threshold of seizure in pts with anorexia nervosa
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| MAZI
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i agree with PHENELZIN
because the high risk drug interaction between MAO inhibitor and TCA, I THINK.
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