general malaise Forum Guru

Topics: 14 Posts: 433
| | 05/03/06 - 01:55 PM  
 
   
 
|   #3 |
B?
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| surgery Forum Junior
Topics: 0 Posts: 30
| | 05/03/06 - 01:58 PM  
 
   
 
|   #4 |
I guess it is B as antagonist has more affinity to bind with receptor
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| robin082006 Forum Hero

Topics: 471 Posts: 5,123
| | 05/03/06 - 03:58 PM  
 
   
 
|   #5 |
B
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| drpkaur Forum Guru

Topics: 196 Posts: 810
| | 05/03/06 - 06:44 PM  
 
   
 
|   #6 |
B
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| mjl1717 Forum Hero

Topics: 958 Posts: 5,465
| | 05/03/06 - 08:03 PM  
 
   
 
|   #7 |
once again (after the fact ) b looks correct my thinking being that a partial agonist could be an antagonist because [it has great affinity but little efficacy] eg. morphine and pentazocine. If its close to y axis it has high affinity for receptor/ efficacy think about height in a graph. Most of time antagonism is competiive eg. Norepi and propanolol at beta 1 receptors. hope this helps
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| HILFIGER Forum Senior
Topics: 22 Posts: 195
| | 05/05/06 - 07:52 AM  
 
   
 
|   #8 |
Thank you very much I think B is correct. I agree with mjl1717, according to katzung most antagonists are actually partial agonists.
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| mjl1717 Forum Hero

Topics: 958 Posts: 5,465
| | 05/05/06 - 07:56 PM  
 
   
 
|   #9 |
great deduction Hilfer. Good q in that it covered efficacy, potency, affinity ,antagonist, agonist, and it makes one invision a graph.
___________________ Smell the coffee! "Is That an Osler move??"
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