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Kaplan Qbank USMLE



Author11 Posts
  #1

43. A bacterium harboring a 15,000-base pair (bp) plasmid that encodes resistance to tetracycline and ampicillin segregates mutants that lose resistance to either drug. Each independent mutant plasmid appears to increase in size by approximately 5200 bp. Which molecular event best explains these findings?



A) Formation of plasmid concatemers



B) Formation of pyrimidine dimers



C) Homologous recombination



D) Insertion of a transposon



E) Slip-stranded DNA replication errors



Please Explain your answer! smiling face
Thanks.


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  #2

d?

  #3

D

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  #4

D

  #5

I agree with D as well.

Can we compare C and D?

How do bacterial usually gain resistance genes? Conjugation, transformation, or transduction?


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Our greatest glory is not in never falling, but in rising every time we fall.

  #6

C

D doesn't make sense!


  #7

i wud choose c as it seems to be a better explanation...can any one eplain this for sure

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  #8

Could you explain why D does not make sense

  #9

C or D?

  #10

I'd say its D... the mutant plasmid is bigger, so it has to have new material... homologous recombination is an exchange of same amount of genetic material, so the plasmid wont be increased in size... does someone agree??

  #11

Preliminary answer
C) Homologous recombination
Will soon come up with Explanation

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