vallia
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A physician from the united states goes to a hospital in Africa, During his first week at the clinic he is told that he will be seeng a patient with G6PD deficiency . Which of the following will be the most likely clinical presentation of the patient?
A. a 6month old child who develops severe anemia following a respiratory tract infection
B. A child who develops hemoglobinuria following a meal of beans
C. a neonate with an enlarged spleen and severe anemia
D. an adult who develops anemia following use of an antimalarial drug
E. An adult who develops severe shortness of breath during an airplane ride
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| star1
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D
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| doc179
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D
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| general malaise
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D
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| robin082006
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D
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| vallia
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I answered the same but it's not D
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| mjl1717
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is it answer-b with the fava beans??
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| general malaise
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hmmm....if not d than B? from fava beans?
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| robin082006
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If D is not the answer, the only other is B
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| doc179
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yes
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| vallia
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yes it's B
in Africa the classic presentation of an G6PD deficiency is a child who eats a meal of beans(Vicia fava) and several hours later develops Hb -uria and peripheral vascular collapse secondary to intravascular hemolysis as a result of oxidant injury initiated by the fava beans. the episode ussualy resolves spontaneously several days later.
In developed countries it's answer D.
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| drbin
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B
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| krsna
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but in kaplan notes pathology its given as...african form is seen with anti-malarial drugs...n the other form with fava beans??i too did the ques and ans it as D....
pls clarify
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| vallia
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I am really confused myself, krsna. the question was from qbank and the given answer is B with this explication.
I was looking on the internet and it seems that fava beans is not planted in africa , but in the Mediterranean zone. That means that the correct answer is indeed D.
I really am sorry for confusing people and if somebody knows more about this matter please share.
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| general malaise
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robbins also says fava bean consumption is also more predominant in meditarrenean, middle east and parts of africa but it doesn't say which is the more common presentation. i think this is one of those unfair qbank questions that i sometimes see.
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| mjl1717
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thats kind of an interesting, slick q-vallia:
underdeveloped country -no meat for child, beans .
developed country-{not written in stone} but able to travel and afford antimalarial drugs.
also in Africa sickle cell disease may protect against some forms of malaria-so how much are antimalarials actually given in Africa.?{but Im not saying they are not given}
good discussion guys and gals
Edited by mjl1717 on 05/02/06 - 04:29 PM
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