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Kaplan Qbank USMLE



Author13 Posts
  #1

inactivation of the Na+/K+ pump will cause
a. an increase in the intracellular volume
b.an increase in the intracellular potassium concentration
c. hyperpolarisation of the membrane potential
d.an increase in the excitability of nerve cell
e. an increase in the flow of sodium out of he cell

  #2

a

  #3

why not C?

  #4

A ITS THE MECH OF REVERSIBLE CELL INJURY DUE TO ATP DEPLETION

  #5

Agree with Yasmeen Anod

  #6

what about d :

increase extracellular K+_____K+influx_______depolarization of the cell________ the cell becomes more excitable


  #7

Na+ goes in and K+ goes out, you can't think only of effect of K+ when you know that Na+ also has sth to do there (Na/K ATPase inactivation affects both Na and K); so it's A (Na/K pump is known as the main security factor for intracellular volume maintainance)

  #8

after i sent my post,i was still thinking about the q, i agree increasing intracellular Na+ will attract more H2O intracellularlly leading to osmotic damage.

  #9

A...Na/K pump is necessary to prevent the cell from swelling up

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"El respeto al derecho ajeno es la paz" Benito Juarez

  #10

Why not d?
Intracellular Na+ goes up, na+/ca++ exchang goes down, intracellular ca++ goes up, neurotransmitter release goes up----increased excitability of neural cells

  #11

IF WE INACTIVATE PUMP Na will remain inside, also there will not be K+ influx

increase in intracellular volume


  #12

A. Agree with aim

  #13

aim.u r making absolute sense.......a is the rite answer,,,

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