DrVirgo
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32. A 4-year-old boy has had constipation and painful defecation since birth. Impacted fecal matter is palpable in the lower abdomen. Examination of tissue obtained on biopsy of the rectum shows absence of cells of the myenteric plexus. The most likely cause is a defect in which of the following developmental events?
A) Alar plate maturation
B) Anterior neuropore closure
C) Neural crest migration
D) Paravertebral ganglion formation
E) Posterior neuropore closure
F) Recanalization of the bowel
C? Hirschprung's Disease? Galglionic cells develop from Neural Crest.
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| DrVirgo
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Is Downs Syndrome assoc. with Hirschprung Disease?
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| robin082006
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Yeah Hirschprung, C
Is Downs Syndrome assoc. with Hirschprung Disease? yes, very often
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| DrVirgo
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Thanks. 
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