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Kaplan Qbank USMLE



Author4 Posts
  #1

40. The diagram shows a liver lobule. Long-term destruction of the hepatocytes, collapse of the histologic architecture, and production of fibrous material in the areas indicated by the arrow is most likely to result in which of the following?





A) Decreased intestinal motility

B) Gallstones

C) Increased central venous pressure

D) Increased hepatic venous pressure

E) Increased portal pressure







E??


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  #2

E?

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  #3

i think also E. any kind of liver damage (MC being Alcohol) eventually causes backward hypertension (i.e. Portal).

besides, C+D are essentially the same.


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  #4

Yes, agree... Due to fibrosis, back pressure will result in increase pressure in the Portal Vein.
(blood flows from Periphery of liver lobule- hepatic artery and portal vein to central vein) so fibrosis inbetween would lead to increase pressure in the Portal vein (and also hepatic artery I think)
Correct?




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