dipti
Forum Elite
Topics: 32
Posts: 237
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35-year-old woman at 18 weeks' gestation has an increased serum α-fetoprotein concentration. Which of the following has the greatest influence in determining the predictive value of this test for neural tube defects?
A) Concentration of α-fetoprotein in maternal serum
B) Maternal history of monozygotic twin pregnancies
C) Prevalence of neural tube defects in the population in question
D) Sensitivity of the test
E) Specificity of the test
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| robin082006
Forum Hero
Topics: 471
Posts: 5,125
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C
PPV is greatly affected by prevalence
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| r_albayunen
Forum Senior
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Posts: 218
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C. true ... the higuer the prevalence the greater the PPV
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