ralux
Forum Senior
Topics: 5
Posts: 59
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Can someone explain me why in addison disease" insufficient glucocorticoids lead to an inability of the kideny to excrete a water load."(kaplan)
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| star1
Forum Guru
Topics: 93
Posts: 826
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For unknown reason that are not well understood, when cortisol is deficient.. a decrease in plasma osmolality fail to supress the ADH secretion . Thus in ppl with cortisol deficiency, a water load may require 24 hour or more to be excreted. Normally it is excreted in 2- 3 hours
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| ralux
Forum Senior
Topics: 5
Posts: 59
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thank u
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