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Kaplan Qbank USMLE



Author7 Posts
  #1

12. A child presents with severe growth failure, accelerated aging that causes adult complications such as diabetes and coronary artery disease, and microcephaly (small head) due to increased nerve cell death. In vitro assay of labeled thymidine incorporation reveals decreased levels of DNA synthesis compared to controls, but normal-sized labeled DNA fragments.The addition of protein extract from normal cells, gently heated to inactivate DNA polymerase, restores DNA synthesis in the child's cell extracts to normal. Which of the enzymes used in DNA replication is likely to be defective in this child?

a. DNA-directed DNA polymerase

b. Unwinding proteins

c. DNA polymerase I

d. DNA-directed RNA polymerase

e. DNA ligase


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  #2

E?

  #3

cconfused

  #4

try again, both of you, thanks

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  #5

B? they have added some proteins and inactivated DNA polymerase.

  #6

YES B IS THE ANSWER

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  #7

I 'm kinda confusedconfused are you talking about SSB proteins? cause they are not enzymes , or is something else?

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