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Kaplan Qbank USMLE



Author14 Posts
  #1

A 25-year-old male patient is experiencing inability to swallow and has speech difficulty. The patient was in perfect health prior to the consumption of home-canned green beans. Which one of the following is the most appropriate treatment?

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1) Administration of staphylococcal enterotoxin antiserum.



2) Penicillin administration.



3) Immunization with Staphylococcus aureus enterotoxin toxoid.



4) Administration of tetanus toxoid.



5) Placement of the patient in a hyperbaric oxygen chamber


  #2

5

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  #3

The patient has Botulism (clostridium botulinum)- give him Penicillin stat -2.

I guess 5 wud be appropriate if he had Gas Gangrene- also caused by Clostridium. but this one is Cl. Perfringens


  #4

right, this patient has botulism which is seen after ingestion of home canned foods with low acid content like green beans, corn, beet. the organism involved is clostridium botulinum.

but frankly i do not know the treatment from the given options. i thought that the treatment was the antitoxin , respiratory/ventilatory support and purging the toxin out of GIT and enema's.

determine, sorry for not been able to reply back. i shall do it tomm.


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  #5

I think it is 5. As far as I know Peniciline is given for wound botulism. First thing to concider in treatment should be respiratory support. But I`m not sure if it means hyperbaric O2?

No problem achilles, pls take your time.


  #6

its penicillin.hyperbaric oxygen is given for gas gangrene


  #7

5. I don't think penicillin is helpful unless it's a wound botulism. Apparently food is already long digested and absorbed and toxin is already attached to peripheric nerves. Treatment should be intubating the patient and giving antitoxin. Since it's not mentioned in options, hyperbaric oxygenation is chosen(it's logical to use to create higher concentration of oxygen to make aerobic conditions).
I also want to choose teatnus toxoid, because the toxin is similar to botulinic, but has diffenet effect -spasm instead of flaccid paralysis. May be it will concur with botulinic toxin and work like concurent antagonist??? What do you think, guys?

  #8

Sorry, I meant tetatnus toxoid, not toxin.

  #9

isnt it 5 ?

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If you think you can You can! If you think you cant you are right again!!

  #10

I'm in doubts, coz although it's logical, I couldn't find anywhere in literature about on hyperbaric oxygenation in botulism. All I found is what I knew-penicillin is exercising in futility unless it's wound botulism.Definitive Tx-botulinic antitoxin. Meanwhile, I'm exploring the possibility of tetanus toxoid. What do You, guys, think?

  #11

2

The correct answer is 2.

I have all the answers from this set of questions. They came from the review courses at Kingston, Ontario. They used to give out questions without answers


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  #12

AAAAA. PENICILIN FOR WHOM REASON
this toxicity is from ingestion of toxin and notfrom organism

  #13

It is 5. Do ABCs first.


  #14

Treatment of food-borne botulism consists primarily of 1) removing any unabsorbed toxin in the digestive tract, 2) neutralizing the circulating toxin with an antitoxin as quickly as possible, and 3) keeping a patient breathing by a mechanical respirator (iron lung) as necessary. Recovery may take several weeks to months.

I dont understand how penicillin will help in this situtation? Can someone explain








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