hey, try this question

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hey, try this question

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15 Posts

nadiabarati

04/14/06 - 04:46 PM

Person is transfused with RBCS for a chronic anemia and devopls bilirubinemia and slight increase in lactate dehydrgenase. What would you see on peripheral blood smear: A. Complement protein C3bi bound to monoctes
B. Degranulated neutrophils
C. Erthrocyte ghosts
D. HLA DR upregulation in circulating CD3 lymphocytes
E. Ig bound to erthrocytes
F. Nucleated erythrocytes

general malaise
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04/14/06 - 05:01 PM

C?

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disha
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04/29/06 - 06:27 AM

ramo7
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04/30/06 - 02:45 AM

yasmeen
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04/30/06 - 03:42 AM

F AFTER HEMOLYSIS RETICULOCYTE COUNT INC AS COMPENSATION FROM MARROW

robin082006
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04/30/06 - 10:02 AM

How about E?

immune hemolytic anemia after blood transfusion.

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tolito
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04/30/06 - 10:29 PM

the high lactate dehydrogenase suggests it was old blood transfused so i will go with c.

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pocas
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04/30/06 - 11:16 PM

yasmeen
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05/01/06 - 11:16 AM

FOR E WON,T U REQUIRE COOMBS TEST OR ONLY BLOOD SMEAR WILL SUFFICE? WHY IS F WRONG?

r_albayunen
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05/01/06 - 08:48 PM

#10

E .. but yasmeen is right about Ret Count on F confused

nadiabarati

06/12/06 - 01:15 PM

#11

it says in blood smear!!! you can not see Ig in blood smear.

So I say F

tolito
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06/12/06 - 06:30 PM

#12

this is a case of post transfusion hemolysis as evidenced by the bilirubinemia and slightly high LDH. i think it is C cos erythrocyt ghosts are seen after hemolysis.

i dont think it can be F because nucleated erythrocytes are rarely seen ( they are not reticulocytes) they are seen following acute severe anemia eg from severe hemolysis ( bilirubin and LDH will be high), or metastatic cancer to bone???? please correct me.

i got a good site with a nice simple discussion i cannot seem able to post the link.

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tolito
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06/12/06 - 06:31 PM

#13

well here it is.

scroll all the way down to 'other cells in periph blood'

http://web2.airmail.net/uthman/blood_cells.html

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alexaE
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06/13/06 - 10:04 AM

#14

id say E, im not sure but cant you see IgGs with immunofluorescence?
its a chronic anemia reticulocyes would not be too high

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bactitech
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06/13/06 - 07:22 PM

#15

Why was this question posted in microbiology in the first place???? Seems to me it's a Hematology question.....

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